4Clinics is a Contract Research Organization (CRO) providing Data management, Safety, Biostatistics, Scientific Writing, Regulatory Affairs and Clinical Operations services for clinical, observational and epidemiological studies with a particular expertise in vaccines, immunotherapeutics and medical devices.
Our CRO structure has put into place specific procedures and dedicated teams and operates in full compliance with such rigorous standards as ICH, 21 CFR part 11.
4Clinics provides comprehensive clinical expertise to meet the needs of its clients. It has long experience of clinical trials, allied methodologies and healthcare, and takes pride in giving its clients satisfaction.
4Clinics benefits from the Research Tax Credit agreement (“Credit Impôt Recherche”).
Xavier Ghyssens (M.Sc.) - Chief Executive Officer
Xavier obtained a Masters Degree in Physics and subsequently went on to obtain a Degree in Finance from the Université Catholique de Louvain(UCL). He founded All4it Groupe in 1998. He had a vision: all companies have a hidden wealth of information in their files – in fact, their own “goldmine” of information - which is not exploited to the fullest. He set up All4it and 4Clinics with the aim of perfecting client-oriented data “goldmining”.
Anne Hepburn (PhD in Medical Biology) - Medical Writing & RA Director
Anne has been Director of Scientific Writing & Regulatory Affairs Services at 4Clinics since 2006. She is a native English speaker and came to 4Clinics with nearly 20 years of experience in clinical research and regulatory affairs. She has extensive experience in preparing clinical trial documentation (protocols, investigator brochures, study reports) and regulatory submissions. She has also written or co-written peer-reviewed articles for pre-clinical and clinical studies.
Mohamed Amakrane (M.Sc.) - Biostatistics Director
A Mathematics background together with 5 years of academic experience in applied statistics and worked as a Statistician and Project Statistician at IDDI from 2003 to 2005 before joining 4Clinics.
David Darcaigne (B.Sc.) – Data Management Coordinator
David has a bachelor’s degree in Bio medical Sciences from Université Catholique de Louvain (UCL). He has more than 9 years of experience in Data Management services and joined 4clinics in 2006.
Christophe Grenot – Director Clinical Operations
Christophe is Clinical Research professional with 20 experience in conducting EU and FDA-regulated trials in a broad range of therapeutic areas. He started his career as nurse in various specialized services before joining the medical device industry at Johnson & Johnson Interventional Systems (now Cordis) as a clinical monitor and clinical research associate. He then joined MedPass International, a full service medical device CRO, where he held the positions of Project Manager, Sr PM, and spend 7 years as the Director of Clinical Operations. He led a number of successful clinical projects for start-ups at the forefront of technological advances. Before joining 4Clincs in 2017, he provided independent consulting services for 4 years to medical device industries in designing, setting up and following clinical development programs.
Mehdi Chelbi (M.Sc.) - Business Development Director
Mehdi graduated in biology from the Lyon 1 and Lille 1 universities. He has 12 years of experience in Business Development and International Sales Management in life science. His client-oriented culture ensures the establishment of a high quality and sustainable relationship with pharmaceutical, biotechnology and life science companies. In his former position, Mehdi was business development manager for a CRO providing preclinical and drug discovery services. He interacted with research labs, biotechnology companies, healthcare and pharmaceutical companies.
ARIANNE offers scientific expertise in clinical and non-clinical development, US and international clinical operations, and strategic regulatory guidance. ARIANNE’s commitment is to further drug development by adeptly working in today’s shifting environment.
ARIANNE offers to its clients the ability to conduct clinical trials (Phases 1 to 4) in North America, Europe, and emerging economies in Asia, Central America and Africa to allow for rapid patient recruitment/retention while remaining cost effective. ARIANNE has experienced regulatory personnel in all countries where it offers its services to comply with international government guidelines and project timelines.
I-REIVAC is the only French network for clinical research in vaccinology. Under the aegis of the ITMO Public Health (AVIESAN), it has been labeled a network of excellence within the framework of the F-CRIN project.
The network is part of the Vaccinology Research Consortium (CoReVac) created by the Institute of Microbiology and Infectious Diseases (IMMI)